The Composition of West Nile virus Lipid Envelope Unveils a Role of 1 Sphingolipid Metabolism on Flavivirus Biogenesis
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چکیده
word count: 235 14 Text word count: 6,958 15 #Address correspondence to Francisco Sobrino, [email protected]; Juan-Carlos 16 Saiz, [email protected] 17 M.A.M.-A. and T.M.-R. contributed equally to this article. 18 F.S. and J.-C.S. are joint senior authors on this work. 19 20 JVI Accepts, published online ahead of print on 13 August 2014 J. Virol. doi:10.1128/JVI.02061-14 Copyright © 2014, American Society for Microbiology. All Rights Reserved. on O cber 8, 2017 by gest http/jvi.asm .rg/ D ow nladed fom
منابع مشابه
The composition of West Nile virus lipid envelope unveils a role of sphingolipid metabolism in flavivirus biogenesis.
West Nile virus (WNV) is an emerging zoonotic mosquito-borne flavivirus responsible for outbreaks of febrile illness and meningoencephalitis. The replication of WNV takes place on virus-modified membranes from the endoplasmic reticulum of the host cell, and virions acquire their envelope by budding into this organelle. Consistent with this view, the cellular biology of this pathogen is intimate...
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